Noble Compression Test | ITB Syndrome Iliotibial band syndrome (ITBS) or iliotibial band friction syndrome is a common overuse injury typically seen in endurance athletes such as runners or cyclists and is thought to be caused by friction of the distal iliotibial band against the lateral femoral condyle, compression of the fat pad and connective tissue deep to it, or inflammation of the bursa. A systematic review by van der Worp in 2012 reports that there is limited or conflicting evidence on wh