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Endometriosis results in changes to your ECS (endocannabinoid system) like less CB1/CB2 receptors and more endogenous cannabinoids. However, this compensation isn’t typically enough for the amount of pain women are in- especially throughout varying points in their cycle. Plant medicine can help supplement the body and balance the ECS- and yes like may chronic pain sufferers this typically looks like a much larger dose than what other medical needs may require. Thanks for continuing to be a light
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Medicine Mondays: Cushing’s Disease, Part 2 Now that we’ve talked about how to diagnose Cushing’s, Part 2 is all about differentiating the two main forms. Most dogs have pituitary-dependent Cushing’s, where a pituitary tumor overstimulates both adrenal glands. A smaller percentage have adrenal-dependent disease, caused by a cortisol-secreting adrenal tumor acting independently. In this video, I walk through how we tell the difference using hormone testing patterns, endogenous ACTH, and imaging,
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“You Won’t Make it to 1” #wait. Sources- PMID 15277908 alissacgore on TT The MC1R gene regulates melanocortin receptors, which also interact with endogenous opioids and modulate pain signaling pathways in the brain and spinal cord. As a result of loss-of-function MC1R variants, individuals may display altered pain thresholds and altered pain sensitivity. These genetic variations also affect neuronal pathways that govern sedation and consciousness, altering how the body responds to anesthetics. T
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