Histone chaperones also participate in the selective deposition of histone variants, which are functionally distinct from canonical histones. For example, HIRA is a chaperone that …

A histone is a type of protein that plays a critical role in the structural organization and regulation of DNA within the nucleus of eukaryotic cells.

2 days ago · A histone is a protein that provides structural support for a chromosome. Each chromosome contains a long molecule of DNA, which must fit into the cell nucleus.

Aug 22, 2025 · When DNA is damaged, histone modifications can help make affected DNA regions more accessible to repair enzymes. For example, specific histone modifications can …

Histone modifications have been implicated in maintaining the transcriptionally poised state of important genesin embryonic stem cells. Histone modifications are believed to be responsible …

A protein that is part of the histone family of basic proteins which associate with DNA in the nucleus and help to condense the DNA into a smaller volume.

May 4, 2025 · The histone family consists of five main classes: H1 (linker histone) and the core histones H2A, H2B, H3, and H4. Core histones form an octamer composed of two H2A-H2B …

histone (HIS-tone) A type of protein found in chromosomes. Histones bind to DNA, help give chromosomes their shape, and help control the activity of genes.

Histone proteins are highly conserved among all eukaryotes. They have two important functions in the cell: to package the genomic DNA and to regulate gene accessibility.

Collectively, it is thought that histone modifications may underlie a histone code, whereby combinations of histone modifications have specific meanings. However, most functional data …