San Francisco 49ers running back Christian McCaffrey reflects on getting a win vs. his former team, the Carolina Panthers.

San Francisco 49ers running back Christian McCaffrey had a memorable performance against his former team, Carolina Panthers, ...

Watch the best plays from San Francisco 49ers running back Christian McCaffery's 142-yard game against the Carolina Panthers ...

San Francisco 49ers head coach Kyle Shanahan gives remarks following the Week 12 matchup vs. the Carolina Panthers.

San Francisco 49ers kicker Matt Gay connects on a 29-yard field goal to extend the 49ers lead over the Carolina Panthers to ...

Carolina Panthers quarterback Bryce Young's pass to wide receiver Tetairoa McMillan is intercepted by San Francisco 49ers ...

San Francisco 49ers quarterback Brock Purdy's play-action pass finds the wide open tight end George Kittle for a 19-yard ...

San Francisco 49ers running back Christian McCaffrey bursts upfield for a 17-yard run into Carolina Panthers territory.

Carolina Panthers quarterback Bryce Young executes the RPO to perfection as he hits wide receiver Jalen Coker over the middle ...

Highlights from the Week 12 matchup between the Carolina Panthers and the San Francisco 49ers during the 2025 NFL season.

Watch the top runs from Week 12 of the 2025 NFL season. Highlights from the Week 12 matchup between the Carolina Panthers and ...

Highlights from the Week 12 matchup between the Carolina Panthers and the San Francisco 49ers during the 2025 NFL season.