Metagenomic sequencing of stool samples from 225 hospital patients and healthy volunteers reveals the impact of different antimicrobial exposures on the gut microbiome.

We conclude that brain states are shaped by local circuit mechanisms, large-scale connectivity and neuromodulation. A unified multiscale theory of cortical dynamics is relevant not only for ...

This correspondence between brain state and brain responsiveness (statedependent responses) is outlined at different scales from the cellular and circuit level, to the mesoscale and macroscale level.

This potentially valuable cross-sectional longitudinal study leverages high-definition transcranial direct current stimulation to the left dorsolateral prefrontal cortex to examine its effect on ...

Non-invasive recordings using brain electrophysiology provide credible insights into decline in neuronal functioning with age. New approaches are required to translate these results into compelling ...

Two-photon imaging and ocular dominance mapping. A. Optical windows for imaging of two macaques. Green crosses indicate the regions for viral vector injections, and yell ...

Institute of Neuroscience, Howard Hughes Medical Institute, University of Oregon, Eugene, United States ...

This study offers valuable insights into the anatomical and physiological features of cold-selective lamina I spinal projection neurons. The evidence supporting the authors' claims is convincing, ...

Harm and responsibility differentially shape guilt and shame, which in turn drive compensatory behavior to varying extents.

This important study reveals that mitotic release of an ER-microtubule tether is critical for normal mitotic progression. Manipulating CLIMP63 phosphorylation, the authors provide convincing evidence ...

This important study shows that different forms and mixtures of cardenolide toxins in tropical milkweed, especially nitrogen- and sulfur-containing types, change how monarch caterpillars eat, grow, ...

This study provides useful insights into addressing the question of whether the prevalence of autoimmune disease could be driven by sex differences in the T cell receptor (TCR) repertoire, correlating ...