Josh Allen and the Buffalo Bills face the Houston Texans on Thursday night after Allen accounted for six touchdowns in last week's win over Tampa Bay.

The Texans mounted an impressive comeback against the Jacksonville Jaguars in Week 10 and found a way to win in Tennessee last Sunday despite not scoring a single point in the first half, but the Bills are a different kind of test. Buffalo covers the spread in prime time. Pick: Bills -5.5; Under 43.5

The Buffalo Bills and their "X-factors" continue their 2025 NFL season with a matchup against the Houston Texans on Sunday in Week 12 at NRG Stadium. While game plans, coaching, and strategy will play a part, but sometimes a big emphasis will sit with some individual players. In terms of the Bills defense, who could those be?

Davis Mills' strong play generated questions from readers this week ahead of Thursday Night Football against the Bills.

Texans players and staff will wear custom-designed shoes to shine a light on causes and organizations they support.