Many surgeons recommend giving up smoking, alcohol, or drugs before surgery, but researchers have found this may also increase the need for pain medication.

In addition to their role in protein degradation, certain proteinases (for example, thrombin, trypsin and tryptase) are signaling molecules that regulate cells by cleaving proteinase-activated ...

Pain represents the cardinal symptom of osteoarthritis, yet its intensity, quality, and impact vary dramatically among ...

Background: Oesophageal acid infusion induces enhanced pain hypersensitivity in non-acid exposed upper oesophagus (secondary hyperalgesia) in patients with non-cardiac chest pain, thus suggesting ...

Yoga might boost GABA in the brain. Benzodiazepines can increase the activity of GABA receptors but may lead to addiction. Foods with glutamine, like meat and spinach, can help make more GABA.

Abstinent smokers experience increased pain sensitivity during withdrawal, to the point that they often require more pain relief after surgery. Why? New from JNeurosci, Zhijie Lu, from Fudan ...

Many patients with inflammatory bowel disease (IBD) suffer from abdominal pain even between acute inflammatory flare-ups. Altered processing of pain in response to fear may be involved. This is the ...

Neuropathic pain syndromes—pain after a lesion or disease of the peripheral or central nervous system—are clinically characterized by spontaneous and evoked types of pain, which are underpinned by ...