Background Pulmonary hypertension (PH) medical therapies are commonly used as a bridge to balloon pulmonary angioplasty (BPA) ...

Background The Forrester classification remains a cornerstone for assessing haemodynamic status in heart failure, yet its ...

Background Approximately one million individuals live with heart failure in the UK, and clinicians diagnose around 200 000 ...

Background Marfan syndrome (MFS) is associated with progressive aortic and valvular disease requiring cardiac surgery, but ...

Background Chronic total occlusion (CTO) often triggers collateral coronary development, yet the relationship between ...

Objectives To validate the Global Registry of Acute Coronary Events (GRACE) risk score and examine the extent and impact of the risk–treatment paradox in contemporary patients with acute coronary ...

Background Data on the prognostic impact of type A aortic dissection involving the common carotid arteries (CCAs) are scarce. Methods Data on the status of the CCAs were available in 1106 patients who ...

Background Oral anticoagulation (OAC) is key in stroke prevention in patients with atrial fibrillation (AF) but there is uncertainty regarding the optimal timing of OAC (re)initiation after stroke, as ...

Objective Multidisciplinary team (MDT) meetings are central to treatment decisions in aortic stenosis (AS), particularly for borderline or high-risk patients. This study evaluates long-term, ...

Aims Mavacamten, the first approved myosin inhibitor for symptomatic obstructive hypertrophic cardiomyopathy (oHCM), addresses hypercontractility and left ventricular outflow tract (LVOT) obstruction.

‘I know of no single acceptable study that shows a high intake of sugar in a population that is almost entirely free from heart disease.’1—John Yudkin The evidence incriminating insulin and ...

Objectives To assess mid-term outcomes in patients with early silent coronary bypass occlusion. Methods 292 consecutive patients who underwent isolated coronary artery bypass grafting (CABG) between ...