A recent study conducted by researchers at Baylor College of Medicine and Texas Children’s Hospital is the first to identify an underlying mechanism and possible drug targets for a new severe ...

The canonical Wnt signaling pathway. The left panel (A) demonstrates the activated Wnt signaling cascade, while the right side portrays the inhibited Wnt signaling cascade. Wnt binds to the Fz ...

(A) The heatmap showing the differential expression of the Wnt proteins and the Wnt target genes between the GTEx cortex (n = 199) and TCGA-GBM (n = 173) datasets. (B) The spatial transcriptomic data ...

A new research perspective was published in Oncotarget's Volume 14 on February 7, 2023, entitled, "WNT-pathway medulloblastoma: what constitutes low-risk and how low can one go?" Novel biological ...

The same message can be interpreted differently by different individuals -- also among cells. This is shown in a study by researchers who studied cell communication through Wnt signalling, which plays ...

Hepatocellular carcinoma (HCC) is one of the deadliest cancers globally, with increasing incidence and mortality rates. It arises from chronic liver diseases, including hepatitis B or C infections, ...

Researchers have captured images of an enzyme for Wnt lipidation, which is pivotal to human development and cancer and crucial for Wnt signaling activation. The findings shed light on the mechanisms ...

Researchers at the University of Illinois, Urbana-Champaign, developed an approach using blue light to activate the Wnt signaling pathway in frog embryos. The pathway plays a wide variety of roles in ...

Human cells decode dynamics Wnt signals using an anti-resonant filter that suppresses intermediate-frequency inputs and is ...