Engineered antigen-presenting extracellular vesicles (AP-EVs) deliver peptide-MHCII, IL-2, and TGF-β to naïve antigen-specific CD4⁺ T cells, driving their differentiation into Foxp3⁺ regulatory T ...
News-Medical.Net on MSN
Engineered extracellular vesicles enable antigen-specific regulatory T cell induction
A research team at the Nano Life Science Institute (WPI-NanoLSI) and the Faculty of Medicine at Kanazawa University has ...
Explore how engineered extracellular vesicles can enhance antigen-specific regulatory T cells to improve immune response.
The Origin and differentiation characteristics of MSC. MSCs can be derived from various tissues and possess the capacity to differentiate into cartilage, bone, and fat cells. Additionally, MSCs have ...
In most solid tumors, high numbers of regulatory T (Treg) cells are associated with poorer outcomes because they dampen the immune system's ability to fight against a tumor. Subscribe to our ...
A new class of engineered extracellular vesicles induces antigen-specific regulatory T cells, offering a targeted strategy for treating autoimmune and allergic diseases.
AZoLifeSciences on MSN
Engineered EVs offer a modular and clinically adaptable immune-tolerance platform
A research team at the Nano Life Science Institute (WPI-NanoLSI) and the Faculty of Medicine at Kanazawa University has developed a new class of engineered extracellular vesicles (EVs) capable of ...
Prakash Nagarkatti receives funding from the National Institutes of Health. Mitzi Nagarkatti receives funding from the National Institutes of Health. A special group of immune cells known as ...
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