Titin, the largest known protein in the human body, has a full chemical name so long it could take more than three hours to say aloud. Built from systematic chemical nomenclature that lists each of ...

My research is focused on understanding protein function at a molecular level. I am interested in systems that are unique or break the "rules," such as disordered proteins. Our main focus is in the ...

Using new high-resolution imaging techniques, MDC researchers and colleagues have tracked titin, the body's largest protein, in real time throughout its entire lifecycle. The method and results could ...

My research is focused on understanding protein function at a molecular level. I am interested in systems that are unique or break the "rules," such as disordered proteins. Our main focus is in the ...

The largest protein in the human body, titin, enables elastic movements of our muscles, including the heart. Mutations in the titin gene (TTN) that impair this function and lead to heart muscle ...

A multinational study by researchers from the UK, Singapore and Germany has discovered that gene mutations in a protein called titin affect heart function in healthy individuals. It was previously ...

A team at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) has developed an innovative method known as TEVs-TTN, for studying the specific mechanical functions of proteins through their ...

Titin is a high-molecular weight protein (3.0-3.8 MDa) in the sarcomeres of vertebrate striated muscles. A plethora of titin isoforms is expressed from the copy of a single titin gene (on chromosome 2 ...

Titin is a "titanically large" protein—the largest in the human body—which enables elastic movements of our muscles, including the heart. Mutations in the titin gene (TTN) that impair this function ...