T cells may be broadly classified as either helper T cells (Th cells, CD4+) or cytotoxic T cells (Tc cells, CD8+). In 1986, T.R. Mosmann, R.L. Coffman, and colleagues observed that individual clones ...
Volume 11, Issue 30 of Oncotarget reported that previously, the authors showed that anti-estrogen drugs combined with a dendritic cell-based anti-HER-2 vaccine known to induce strong Th1-polarized ...
Increased inflammation via cytokine storms has led to multiple heart complications in coronavirus disease 2019 (COVID-19) infections. But in order to treat these cardiovascular problems, doctors will ...
Inflammatory bowel disease (IBD) combines several chronic disorders of the gastrointestinal tract including Crohn's disease (CD), ulcerative colitis (UC), and indeterminate colitis (IC). In recent ...
An IL-4-Independent and CD25-Mediated Function of c-maf in Promoting the Production of Th2 Cytokines
c-maf is a T helper (Th)2 cell-specific transcription factor, which promotes the differentiation of Th2 cells mainly by an IL-4-dependent mechanism. It remains unclear whether c-maf possesses any IL-4 ...
Each well of a 96-well SearchLight array is spotted with two to nine target-specific antibodies. For instance, the company's human Th1/Th2 cytokine array detects interleukins (IL)-2, 4, 5, 8, 10, ...
Stem cells hold immense therapeutic potential due to their self-renewal capacity and ability to differentiate into various cell types. Mesenchymal stem cells (MSCs) are multipotent stem cells derived ...
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