Forbes contributors publish independent expert analyses and insights. In a previous installment, we described an alternative cell treatment which relies on synNotch receptors. These synthetic ...

Add Yahoo as a preferred source to see more of our stories on Google. To bring the benefits of immunotherapy to more patients, scientists have turned to synthetic biology, a new field of study that ...

Most cancer treatments—from chemotherapies to engineered immune cells—have a host of side effects, in large part because they affect healthy cells in the body at the same time as targeting tumor cells ...

The synNotch receptor allows scientists to precisely control when and where the therapeutic T cell is active. "These smart cell therapies can unleash potent therapeutic activity precisely at the site ...

University of Pittsburgh researchers have developed a universal receptor system that allows T cells to recognize any cell surface target, enabling highly customizable CAR T cell and other ...

T-cell therapies work well for blood cancers, but they come with caveats—a major one being that they’re cumbersome and expensive to tailor to a patient’s specific cancer type. On top of that, the ...

BioWorld - Wednesday, April 2, 2025 Breaking News: BioWorld by Clarivate releases comprehensive 2024 year in review See today's BioWorld Science Home » New conditionally replicative adenovirus vector ...

a few months ago, a scientific group published two papers in the journal Cell regarding a very archaic cell surface receptor named Notch. Paper 1: Morsut et al. "Engineering Customized Cell Sensing ...

Bladder cancers (BCs) that invade the muscle layer are classified as muscle-invasive bladder cancers (MIBCs). The MIBC subtype accounts for around 25% of all BC cases, with a significant proportion of ...

University of Pittsburgh researchers have developed a universal receptor system that allows T cells to recognize any cell surface target, enabling highly customizable CAR T cell and other ...

Researchers undertook a systematic analysis of the molecular building blocks used to engineer therapeutic cells. Their work resulted in a comprehensive rule book for the design of therapeutic cells ...