Massively parallel DNA sequencing technologies provide exponential increases in the amount of data returned from the sequencing process, relative to traditional (Sanger-based) techniques. Use of ...

Since the illnesses an individual experiences in a lifetime are largely determined by their genetics, there has been significant interest to better understand our genetic makeup for years. Our ...

Genome editing in vivo requires safe and efficient delivery of reagents to a target tissue. At the same time, delivery to non-target tissues, especially germline cells, must be assessed for potential ...

A team of researchers has developed a software tool that provides a way for the safer design of genome editing in all organisms with a transcriptome. For about a decade, researchers have used the ...

MIT scientists have found a way to make gene editing far safer and more accurate — a breakthrough that could reshape how we treat hundreds of genetic diseases. By fine-tuning the tiny molecular “tools ...

The ability of CRISPR gene-editing technology to safely modify human embryos has been cast into doubt after several recent papers described massive disruptions to DNA in embryos subjected to editing.