The San Francisco 49ers have lost two defensive ends in the last 24 hours, as the second one announced his retirement on ...

The San Francisco 49ers are signing LB Dre Greenlaw to a one-year deal. Here's how Greenlaw fits (back) into San Francisco's ...

Odighizuwa will bolster a thin San Francisco defensive line. He recorded 52 pressures last season, more than all five Niners ...

The San Francisco 49ers may soon move on from wide receiver Brandon Aiyuk. After months of trade discussions that went ...

A stabbing in San Francisco's Chinatown caught on camera on Thursday left the victim severely injured, and a suspect was ...

San Francisco's city charter spans more than 500 pages and is among the longest municipal charters in the country. Lurie said ...

Though the reason for the purchase isn't known, there's speculation that the mansion could be turned into a foreign consulate ...

"We've gone through so much." ...

Former Jets, Eagles and 49ers defensive end Bryce Huff has announced his retirement after six seasons in the league.

Another week, another artificial intelligence company lease in downtown San Francisco.  AI software firm Hex Technologies ...

"We have lost money year over year at this location." ...