In the past several years, Rockefeller University's Kivanç Birsoy and his team in the Laboratory of Metabolic Regulation and ...
Every cell in the human body runs a protein-folding factory inside a compartment called the endoplasmic reticulum, or ER.
Protein folding is a critical process by which linear chains of amino acids adopt specific three‐dimensional conformations essential for biological function. In recent years, studies have increasingly ...
How does the ER prevent misfolded proteins? Researchers identify the SLC33A1 transporter as a critical glutathione regulator ...
The strategies biopharmaceutical manufacturers currently use to limit protein misfolding are complex, time-consuming, and generate low yields with only limited scalability. Covalent organic frameworks ...
This Collection invites submissions which advance our understanding of the mechanisms of protein misfolding and clearance, and interventions directed at reducing protein aggregates. Quaternery ...
Rockefeller researchers previously discovered several new important tasks that the antioxidant glutathione manages throughout the body. Now they’ve found that glutathione maintains the smooth ...