A structurally tuned HPV cancer SNA vaccine boosts CD8⁺ T‑cell responses and slows tumor growth in mice and patient‑derived spheroids, a study shows.

DNA, the blueprint of life, is best known for its fundamental role as genetic material—storing and transmitting biological information through the precise sequence of its bases. For decades, this ...

Nucleic acids are complex biological molecules that store and transmit genetic information in all living organisms. They are essential for the survival and reproduction of life on Earth. The two main ...

In 1869, Swiss scientist Friedrich Miescher isolated a mysterious substance from cell nuclei—an overlooked finding that would ...

The findings will be published today (February 11) in Science Advances.

New findings from Karolinska Institutet reveal how the gene HNRNPU coordinates several fundamental molecular processes during ...

To obtain high-quality, purified nucleic acids, scientists can use several different methods, including phenol-chloroform extraction, cesium chloride/ethidium bromide (CsCl/EtBr) gradient ...

Since the discovery of the double-helical structure of DNA and postulation of the central dogma of molecular biology, stating that the flow of genetic information goes from DNA to RNA to protein, the ...

Explore how HPV tumours are targeted by innovative vaccine designs that enhance immune response against cancer effectively.

Drug regulatory authorities in various countries have established stringent limits on the residual nucleic acids in biological products. For example, the FDA mandates that the residual DNA in ...

LL-37 continues to attract scientific interest due to its unique structural characteristics and its diverse interactions within biological systems. As the only known cathelicidin-derived peptide, LL-3 ...