Scientists have uncovered a surprising new way the immune system fights cancer, overturning a core belief that has guided ...

Many modern cancer treatments, including immunotherapy, depend on activating killer T cells to recognise and destroy tumours.

The major histocompatibility complex (MHC) comprises two primary classes of antigen-presenting molecules that are essential for adaptive immunity. MHC class I molecules present endogenous peptides to ...

Researchers found that lowering MHC I can expose cancerous or foreign cells to CD4+ T cell attack, reshaping assumptions ...