The cytokine family including interleukin-2 and -15 (IL-2 and IL-15) started out in a primitive vertebrate species with three related cytokines IL-2, IL-15, and IL-15-like (IL-15L), all sharing ...

Cytokines and their kin, alternatively called interleukins, growth factors, interferons, necrosis factors, and others, are soluble messengers responsible for communication between nearby cells, ...

Cytokines are a large group of bioactive small molecule proteins synthesized and secreted by immune and non-immune cells. There are various types of cytokines that belong to different families and ...

Identifying specific roles for individual cytokines is complicated by the observation that they share common functional subunits. Interleukin-12 (IL-12) is a heterodimer of p35 and p40 subunits, and ...

Does the COVID-19 cytokine storm exist? Inflammatory proteins, also known as cytokines, play a crucial role in the immune response. If this immune response is too strong, a phenomenon known as ...

Cytokines, such as interleukin-2, emerged decades ago as promising cancer treatments. After all, they were the first modern drugs to prove that the immune system could be targeted to treat cancer, ...

Medicenna Therapeutics Corp. specializes in engineered interleukins for oncology and autoimmune diseases, enhancing therapeutic properties and reducing adverse effects. Medicenna Therapeutics' main ...