How many photons are in a Green Fluorescent Protein (GFP)? More than you may have thought. The illumination required to excite fluorophores leads to their gradual photodegradation, a phenomenon known ...

Striking the Right Balance between Signal Strength and Long-Term Cell Health A key challenge with live-cell fluorescence imaging is the ability to visualize weak fluorescent signals over background ...

Prior to the advent of the tools and technologies for live-cell imaging, biologists relied on single snapshots of cellular events to understand how cells function. Yet without the ability to observe ...

A new two-photon fluorescence microscope developed at UC Davis can capture high-speed images of neural activity at cellular resolution thanks to a new adaptive sampling scheme and line illumination.

A fluorescent microscope image shows that in a population of genetically identical. The cell in green is expressing a green-fluorescent protein that is expressed by cells that are able to take up DNA ...

What does the inside of a cell really look like? In the past, standard microscopes were limited in how well they could answer this question. Now, researchers have succeeded in developing a microscope ...

Until today, skin, brain, and all tissues of the human body were difficult to observe in detail with an optical microscope, since the contrast in the image was hindered by the high density of their ...