Immune Checkpoint Blockade (ICB) has revolutionized the treatment of cancers like melanoma, but up to 60% of patients don't ...

Researchers expanded millions of cancer-targeting NK cells from a single donor, improving manufacturing for future therapies.

UT Southwestern Medical Center researchers have discovered that increasing the levels of a protein called BACH2 makes engineered cancer-fighting immune cells behave more like stem cells, improving ...

What if cancer isn’t unstoppable — but the immune system just isn’t fully awake? Scientists at the University of Southampton have discovered a powerful new way to activate cancer-killing T cells. By ...

Scientists uncover a new “recipe” that shows how exhausted T cells can be reprogrammed to regain their ability to attack tumors.

Growing cancer-targeting T-cells in a lab is only half the battle. They must be collected intact. A new IIT Bombay study has demonstrated a gentler recovery method that could improve the reliability ...

CAR T-cell therapy, which transforms patients’ own immune cells into cancer-fighting warriors, has revolutionized how physicians treat cancer, especially blood cancers. “These patients can be cured ...

Tumors are stressful places for cancer-fighting immune cells. Low oxygen, high acid levels, and other stressors put strain on mitochondria, the cell’s energy factories, leading to T cell exhaustion ...

New research shows lymph nodes aren’t just cancer bystanders, they’re the command centers fueling immune attacks. Surgically removing them along with tumors may weaken treatment, while preserving them ...

In a first-of-its-kind clinical trial, UCLA scientists have shown it's possible to reprogram a patient's blood-forming stem cells to generate a continuous supply of functional T cells, the immune ...

Researchers say an immunotherapy they used represents a significant step forward and could lead to new treatment options, even for other forms of cancer ...