UFH is a mixture of glycosaminoglycans of varying lengths (mean 15,000 daltons; range 3000-30,000 daltons). This heterogeneity results in variable anticoagulant activity and pharmacokinetics. In fact, ...

(1) How was this issue identified? Starting in quarter 1 2007, we noticed the high rate of excess dosing for heparin on our ACTION site reports compared to national rates. (2) What did you do to ...

Patients with high D-dimer levels who are hospitalized with COVID-19—but not those who require ICU-level care—stand to gain a reduction in major thromboembolism and death with therapeutic-dose low ...

While efforts to make dosing safer in the wake of recent heparin-related deaths make sense, such efforts have created a fresh set of safety concerns for providers who use it, observers say. For one ...

Anecdotal reports of subtherapeutic heparin have kept many cardiologists across the world on edge over the past couple of months, although no regulatory authority has yet confirmed a specific problem.

SAN FRANCISCO and FLAGSTAFF, Ariz., June 13, 2024 /PRNewswire/ -- Today, InsightRX and Northern Arizona Healthcare (NAH) announced they will make InsightRX's precision dosing software for heparin ...

Despite national attention, heparin overdoses continue to be an issue for hospitals, a fact underscored by a recent case in which 14 babies at a Texas hospital were given a massive overdose of the ...

THE chief obstacles to the wide-scale use of heparin in the treatment of venous thromboembolic disease, are two: the expense of the available commercial heparin preparations and the transiency of ...

Extracorporeal membrane oxygenation (ECMO) technology has relative contraindications in haemorrhagic disease but remains an effective therapeutic option for the treatment of pulmonary haemorrhage ...

PMX-60056 Heptagonist Is The Only Reversing Agent for Heparin and Low Molecular Weight Heparins in Clinical Development PMX-60056 is the Company's Second Clinical Trial Initiation in the Past Month ...