Patients with pathologically confirmed EOC who underwent clinical tumor-normal sequencing from January 1, 2015, to December 31, 2020, inclusive of germline analysis of ≥76 genes were included.

Researchers at Baylor College of Medicine’s Dan L Duncan Comprehensive Cancer Center and Human Genome Sequencing Center investigated the extent to which forms of genetic variation called germline or ...

In a recent study published in the journal PLOS Pathogens, researchers used computational simulations and experiments with murine models to investigate how genetic variations encoded in the germline ...

Please provide your email address to receive an email when new articles are posted on . “Inherited predisposition to myeloid malignancies is more common than previously appreciated,” Fei Yang, MD, ...

From 7% to nearly 9% of patients with advanced cancer were found to harbor a germline variant with targeted therapeutic actionability in the first study of its kind. The study involved 11,974 patients ...

Coordinated germline and tumor panel testing was feasible and revealed P/LP CPG variants in 6.3% of the Pediatric MATCH cohort. Tumor variant fraction, germline association of CPG with tumor type, and ...

Please provide your email address to receive an email when new articles are posted on . Approximately 1 in 7 patients with lung cancer had a pathogenic germline ...

I don't remember the first time I heard the word "germline," but I do remember when it became a major part of my life. I’m not sure when I first heard the term "germline." I’ve always been a bit of a ...

Researchers at Baylor College of Medicine's Dan L Duncan Comprehensive Cancer Center and Human Genome Sequencing Center investigated the extent to which forms of genetic variation called germline or ...