Human karyotype of Down syndrome. Autosomal abnormalities. Trisomy 21. [Rujirat Boonyong/Getty Images] Faulty brain circuits seen in Down syndrome may be caused by the lack of a particular molecule ...

Down syndrome is associated with accelerated aging. It is estimated that up to 90% of individuals with the condition develop Alzheimer's disease before the age of 70. A study by researchers at the ...

A new study identifies distinct molecular and immune subtypes across individuals with Down syndrome, offering new insights that could lead to personalized medicine approaches for the clinical ...

Three copies of chromosome 21 cause Down syndrome (DS), and roughly half of children born each year in the United States with DS—approximately 2,600—also have congenital heart defects (CHDs). What is ...

Scientists are laying the groundwork for treating one of the most common genetic conditions in humans. Research out today highlights a promising new approach to Down syndrome, also known as trisomy 21 ...

Down syndrome and autism spectrum disorder can both involve a need for additional support. However, these are distinct diagnoses with different underlying causes and presentations. Down syndrome (DS) ...

'People tell me I don't "look Down's syndrome enough".' ...

“This study is really exciting because it serves as proof-of-concept that we can target astrocytes, a cell type in the brain specialized for secreting synapse-modulating molecules, to rewire the brain ...