Researchers have made a major breakthrough earlier this year in the field of evolutionary conservation of molecular dynamics in enzymes. Their work points to potential applications in health, ...

WASHINGTON, D.C., February 19, 2018 -- Enzymes are proteins that speed up or catalyze a reaction in living organisms. Bacteria can produce enzymes that make them resistant to antibiotics. Specifically ...

In nature, evolution takes years to sculpt new traits. In the lab, scientists hope to achieve this feat much faster: Being able to evolve proteins with enhanced or novel functions has important ...

Researchers have shown how laboratory evolution can give rise to highly efficient enzymes for new-to-nature reactions, opening the door for novel and more environmentally friendly ways to make drugs ...

Scientists have developed a novel approach to modifying enzymes to improve functionality. They designed a new algorithm to make multiple changes to an enzyme sequence at once as compared to the ...

Enzymes catalyze chemical reactions in organisms - without which life would not be possible. Leveraging AlphaFold2 artificial intelligence, researchers at Charité – Universitätsmedizin Berlin have now ...

Recent trends in directed enzyme evolution focus on combining high-throughput screening methods with advanced biophysical tools and data-driven computational approaches. However, these methods pose ...

Two scientists at The Scripps Research Institute (TSRI), Research Associate John S. Reader, D.Phil, and Professor Gerald F. Joyce, M.D., Ph.D., both of the institute’s Department of Molecular Biology, ...

Some three billion years ago, when life on this planet was still in its infancy, hot springs, geysers and volcanic hydrothermal vents were burgeoning with single-cell organisms. Temperatures hovered ...

Connecticut-based company partners with laboratories to explore how enzymes can break down plastic and textile scrap to make new resins. Protein Evolution says its technique can create rPET resin “is ...

But although the research team had recently used laboratory evolution to improve a designed enzyme by more than 1,000 fold, it was unknown how evolution boosts its activity. Until now. Lead author ...