Daughter cells vary significantly after stress In addition to real-time measurements under the microscope, the researchers examined various endpoints, such as the strength of different stress signals ...

Cells are the smallest units of life. But even within the same tissue or organ, they are not all identical. New variations arise continuously during cell proliferation. While genetic mutations alter ...

A research team from Skoltech, the Institute of Physical, Chemical, and Biological Problems of Soil Science of the Russian Academy of Sciences, and other scientific organizations in Russia and the U.S ...

DNA replication in differentiated cells follows a defined program, but when and how it is established during mammalian development is not known. Here we show using single-cell sequencing, that late ...

Mutations in the global transcriptional activator EP300/KAT3B are being reported in aggressive malignancies. However, the mechanistic contribution of EP300 dysregulation to cancer is currently unknown ...