Cryo-electron microscopy (cryo-EM) has emerged as a cornerstone of structural biology, enabling the visualisation of macromolecules in near-native states with minimal artefacts. Specimens are rapidly ...

Researchers shed new light on G-quadruplexes, a type of secondary DNA structure that has attracted attention as a potential therapeutic target in cancer. Every day, billions of cells in your body ...

Mitochondria are the powerhouses in our cells, producing the energy for all vital processes. Using cryo-electron tomography, researchers at the University of Basel, Switzerland, have now gained ...

The meteoric rise of cryo-electron microscopy from an obscure imaging technique to a powerhouse for determining biomolecular structures is transforming our understanding of biology. Our knowledge of ...

The Cryo-Electron Microscopy Center supports industry, academic, government, and non-profit research institutes, providing single-particle and microcrystal electron diffraction capabilities. We offer ...

In conjunction with the Structural Biology Core Facility, CEMIL enables practitioners of Cryo-EM within MSK laboratories to design innovative experiments and collect the highest quality Cryo-EM data ...

Scientists have developed a new imaging technique that uses a novel contrast mechanism in bioimaging to merge the strengths of two powerful microscopy methods, allowing researchers to see both the ...

Proteins systematically lose their protective hydration shell when their environment becomes more acidic. Until recently, ...

How do we learn to remember? At the most fundamental level, it's all about chemicals and electricity. Beyond their roles in diet and nutrition, calcium and magnesium work as ions, or charged particles ...

As the global push toward a carbon-neutral society accelerates, understanding how microorganisms metabolize methanol with ...

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