What is the best intervention window for someone struggling with cocaine addiction? When he or she is in the middle of a drug binge, or after a period of abstinence when there is temptation to fall ...

Drug addiction is a chronic, often relapsing disorder that affects millions of people worldwide. Despite successful treatment, many individuals struggle to maintain sobriety and may relapse.

When a cocaine addict relapses, it isn't a matter of personal failure—it's the biological result of their brain's rewiring, new research finds. Michigan State University scientists have found that ...

In a study that was originally published late last year, researchers unveiled the risks for former cocaine users who may relapse by taking methylphenidate. Methylphenidate is used as a treatment for ...

New research on the biological basis of addiction has found that the critical epigenetic enzyme histone deacetylase 5 (HDAC5) limits the expression of the gene Scn4b, regulating neuronal activity and ...

This study is led by Prof. Chaoran Ren (Guangdong-Hongkong-Macau Institute of CNS Regeneration, Jinan university), Prof. Tifei Yuan (Shanghai Mental Health Center, Shanghai Jiaotong University School ...

For hundreds of years, craving has been recognized as a central causal feature of addiction and relapse in overeating, gambling, and other addictions. But what causes craving, how one ends cravings, ...

An existing drug currently used to treat glaucoma, altitude sickness, and seizures may also have the potential to prevent relapse in opioid use disorder, according to a study by researchers at ...

What’s the most addictive drug? Newly published research indicates that when focusing on persistent drug memory, craving, and addiction, the most addictive illegal drug is cocaine. In contrast, the ...

Neurons in a specific brain circuit regulating mood are stained in green, and the transcription factor DeltaFosB, found in some of these circuit neurons, is labeled in red. When a cocaine addict ...