(A) Schematic diagram of the experimental system that detects calcium release from the endoplasmic reticulum by each ryanodine receptor. (B) Isoflurane selectively activates RyR1 (mean ± standard ...

IN INFANTS and children the technic of induction of anesthesia demands careful consideration, if optimal results are to be obtained. The success of the induction depends upon several factors, one of ...

Purpose: Product- and patient-specific factors that may influence the selection of an inhaled anesthetic agent are discussed in four case studies. Summary: The cardiovascular, respiratory, hepatic, ...

Analgesics are commonly employed drugs for perioperative procedures and are required for painful procedures. They include not only non-steroidal anti-inflammatory drugs (NSAIDs) but also opioids and ...

Since their anesthetic effects were discovered approximately 180 years ago, inhalational anesthetics have been used for general anesthesia in surgical operations. However, the mechanism of their ...

K.A. is a 45-year-old man withacute pancreatitis who is brought to the operating room from the intensive care unit sedated and intubated for abdominal debridement. K.A. takes no medications and has no ...