Mast cell precursors migrate from the BM to the periphery via CXCR2, BLT1 and/or CYSLT1, another chemoattractant GPCR, signaling. Eosinophils leave the BM via CCR3, while CCR7 is used by mature tissue ...
Chemokines are a large subfamily of small cell signaling proteins or cytokines, which in conjunction with their G protein-coupled receptors (GPCR), govern the process of cell migration. The role of ...