The Chicago Bears are now loaded with weapons on the offensive side of the ball, which is certainly great news for quarterback Caleb Williams heading into his sophomore campaign. But the Bears are lacking in one area: running back.

One of the biggest preseason delights for Chicago has been defensive end Austin Booker, who has four sacks already. After picking up his fourth sack of the preseason in this game against Buffalo, Booker met with the medical staff and then was later ruled out with a knee injury.

The Bills take on the Bears in preseason game No. 2. Stay right here for live updates all afternoon and evening.

The Buffalo Bills (0-1) and Chicago Bears (0-0-1) meet Sunday in Week 2 of the preseason. Kickoff from Soldier Field in Chicago is scheduled for 8 p.m. ET (FOX). Let's analyze BetMGM Sportsbook's NFL odds around the Bills vs. Bears odds and make our expert NFL picks and predictions for the best bets.

The Bears shut out the Bills 38-0, ending a 31-year preseason drought, led by Caleb Williams, strong backups, and stout defense.

NFL Sunday preseason features the Chicago Bears taking on the Buffalo Bills in the late game. This game kicks off on Sunday, August 17, at 5 p.m. PT/8 p.m. ET (6 p.m. MT) with a live broadcast on FOX. WATCH NOW: Chicago Bears vs. Buffalo Bills live for FREE with DIRECTV (free trial).

The Bears host the Bills in NFL preseason action at 8 p.m. ET on FOX, with Chicago's starters expected to take the field.

We've long heard about how Chicago Bears head coach Ben Johnson plans to use multiple tight ends in his offense since GM Ryan Poles selected Colston Loveland in the first round of the 2025 NFL Draft, and in Sunday night's 38-0 preseason win over the Buffalo Bills, we saw that strategy come to fruition.